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Informatics Report Series
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| Title:Metabolic modeling of microbial strains in silico |
| Authors:
M.W. Covert
; C.H. Schilling
; I. Famili
; J.S. Edwards
; Igor Goryanin
; E. Selkov
; B.O. Palsson
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| Date:Mar 2001 |
| Publication Title:Trends in Biochemical Sciences |
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Publication Type:Journal Article
Publication Status:Published
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Volume No:26 (3)
Page Nos:179-186
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DOI:10.1016/S0968-0004(00)01754-0
ISBN/ISSN:0968-0004
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- Abstract:
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The large volume of genome-scale data that is being produced and made available in databases on the World Wide Web is demanding the development of integrated mathematical models of cellular processes. The analysis of reconstructed metabolic networks as systems leads to the development of an in silico or computer representation of collections of cellular metabolic constituents, their interactions and their integrated function as a whole. The use of quantitative analysis methods to generate testable hypotheses and drive experimentation at a whole-genome level signals the advent of a systemic modeling approach to cellular and molecular biology.
- Links To Paper
- sciencedirect
- Bibtex format
- @Article{EDI-INF-RR-0566,
- author = {
M.W. Covert
and C.H. Schilling
and I. Famili
and J.S. Edwards
and Igor Goryanin
and E. Selkov
and B.O. Palsson
},
- title = {Metabolic modeling of microbial strains in silico},
- journal = {Trends in Biochemical Sciences},
- year = 2001,
- month = {Mar},
- volume = {26 (3)},
- pages = {179-186},
- doi = {10.1016/S0968-0004(00)01754-0},
- url = {http://www.nature.com/msb/journal/v3/n1/full/msb4100177.html},
- }
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