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Title:A Graphical Notation to describe the Logical Interactions of Biological Pathways
Authors: Stuart Moodie ; Anatoly Sorokin ; Igor Goryanin ; Peter Ghazal
Date:Aug 2006
Publication Title:Journal of Integrative Bioinformatics
Publication Type:Journal Article Publication Status:Published
The modelling of biological intra-cellular pathways requires the systematic capture and representation of interactions between components that are biologically correct and computationally rigorous. The challenge is two fold, to verify and extend our understanding of such pathways by comparing in silico models to experiments; and to ensure that such models are understandable by biologists and for checking biological validity. In this report we present a graphical notation, the Edinburgh Pathway Notation (EPN), which satisfies the central biologically driven requirements while providing a strict formal framework for analysis. The EPN emphasises the use of a logical representation of pathways, which is particularly suited to pathways were some mechanisms are not known in detail.
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Journal of Integrative Bioinformatics
Bibtex format
author = { Stuart Moodie and Anatoly Sorokin and Igor Goryanin and Peter Ghazal },
title = {A Graphical Notation to describe the Logical Interactions of Biological Pathways},
journal = {Journal of Integrative Bioinformatics},
year = 2006,
month = {Aug},
url = {},

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