Informatics Report Series
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Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells.
Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation.
SUSPECTS: enabling fast and effective prioritization of positional candidates.
Speeding disease gene discovery by sequence based candidate prioritization.
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